The main objective of this project is to identify novel biomarkers for gastric cancer associated with H. pylori infection, and to build a predictive model that allows patient stratification.
To achieve this goal, population-based studies will be carried out. In a first step a case-control study will be established in order to screen and identify risk biomarkers for gastric cancer. In a second step, the identified biomarkers will be validated in a cross-sectional study as well as in a nested case-control study to evaluate the predictive value for gastric cancer and its precursors. Finally, a predictive model for gastric cancer risk will be developed taking into account the results obtained from the screening and validation studies, and environmental co-factors. The establishment of a novel risk profile will be of extremely significance for the follow up and treatment selection of populations at high risk for gastric cancer.
This project is funded by the Deutsche Forschungsgemeinschaft (DFG) and the National Science Foundation China (NSFC).
Professor Kai-feng Pan
Department of Cancer Epidemiology, Peking University School of Oncology (PUSO)
Peking University Cancer Hospital & Institute
No.52 Fu-cheng Road, Haidian District, Beijing 100142, China
+8610-88196937
pan-kf@263.net
http://www.bjcancer.org/Departments/Main/SearchIndex?siteId=21251
Funded by: Federal Ministry of Education and Research (BMBF) | Ministry of Science and Technology of the People’s Republic of China | Beijing Municipal Science and Technology Commission